This study was designed to investigate the anti obesity effect of Pterocarpus marsupium bark extract in female wistar rats fed on cafeteria and atherogenic diets. Obesity was induced in female wistar rats by feeding cafeteria diet/ atherogenic rats daily for 40 days in addition to normal diet ad libitum. Pterocarpus marsupium bark extract was administered in a dose of 800 mg/kg.p.o.per day to the drug treatment groups. The Pterocarpus marsupium bark extract showed significant reduction in body weight, daily food intake, internal organs, fat pad weights and serum glucose, cholesterol and triglyceride levels and increase in locomotor activity in cafeteria and atherogenic diet fed rats when compared with control group of rats.These results indicate that the Pterocarpus marsupium bark extract posses anti obesity effect in cafeteria and atherogenic diet fed rats. The effect produced was comparable with that produced by standard anti obese drug, Sibutramine.
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